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Open. Consensus. Practice. Tools.

Improving openness and interoperability in Public Health Bioinformatics

a global coalition.

Sketch of a globe and a DNA strand, representing the interconnectedness of global genetic information.

Working Groups

The activities within PHA4GE are aligned to its vision of achieving a rapid global genomic-driven public health response to disease outbreaks. Each of these working groups benefit from collaborative work among its members.

Why PHA4GE

Standardized data structures and interchange formats are critical to the development of an open software ecosystem, and will empower more participants to analyze and govern their own data, regardless of resource status.

Enabling Global Public Health to adapt more readily to changing priorities and emerging threats and to promote innovation, collaboration and development from public/private sector.

Well integrated tools are critical to convey actionable information to a range of stakeholders and decision-makers across multidisciplinary public health teams.

Advancing the use of open data and open source software, empowering more laboratories to analyze and govern their own data regardless of resource status.

About PHA4GE

Rapid global genomic driven public health response to disease outbreaks

PHA4GE is a global coalition that is actively working to establish access to flexible, sustainable bioinformatics capacity. This is a critical need for public health laboratories throughout the world as pathogen sequencing becomes more routine.

We have the vision of fostering the development, innovation and collaboration amongst the global public health bioinformatic workforce by reducing barriers to entry.

Funders & Affiliations

We are announcing Pathoplexus, a specialised genomic database for viruses of public health importance. By combining modern open-source software with transparent governance structures, Pathoplexus fills a niche within the existing genomic sequencing database landscape, aiming to meet requests from both data submitters and users and striving to improve equity.

In April and June 2024, we invited all PHA4GE members to participate in a survey to ensure PHA4GE is providing opportunities that align with your passions and expertise. The results have been compiled into a short report.

Marking this year’s Mandela Day, PHA4GE hosted 20  young learners from Heideveld, hoping to inspire them to become tomorrow’s scientists.

A look into how PHA4GE is creating a set of development guides, as well as a database of searchable attributes enabling the assembly of suites for specific use cases and ensuring that relevant terms are re-used, increasing interoperability across the data streams in public health

Our Working Groups continue to showcase their efforts to enhance the interoperability, accessibility, and reproducibility of pathogen genomics data on a global scale.

Wastewater surveillance is a crucial public health tool that involves monitoring the contents of wastewater to gain insights into community health. This method can detect the spread of infectious diseases, track drug use patterns, and assess the effectiveness of public health measures. By analyzing wastewater, health officials can identify outbreaks early, observe disease trends, and allocate resources more effectively, ultimately safeguarding public health.

PHA4GE's Global Genomics webinar series offers insights into the latest research topics and community developments followed by a Q-A session.

We are thrilled to announce a PHA4GE Bioinformatics Pipelines and Visualizations Working Group Webinar, featuring a talk by Kevin Libuit from Theiagen Genomics. Kevin shares the progress made by the working group  on "Best Practices for Public Health Bioinformatics Pipelines".

In this episode, Assistant Professor Ruklanthi de Alwis from Duke-NUS Medical School Centre for Outbreak Preparedness shares her expertise on Pathogen genomic surveillance in Asia.

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