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PHA4GE Newsletter – August 2024

Editorial

Welcome to the third issue of the PHA4GE newsletter for 2024!

We are excited to introduce Pathoplexus, a new specialized sequence database for human viral pathogens. To start off, Pathoplexus applies modern open-source software and transparent governance to enhance data submission, querying, and accessibility to data on five viruses namely, Ebolavirus sudan, Ebolavirus zaire, West Nile virus, and Crimean-Congo haemorrhagic fever virus. To become part of the scientific community that helps drive Pathoplexus, we welcome you to join the PHA4GE Data Repositories Working Group.

In response to recent WHO updates, the Bioinformatics Pipelines and Visualization Working Group is updating a guidance document for Mpox. This living document gives recommendations on open-source tools and resources for public health labs to streamline Mpox data analysis and integration.

The PHA4GE member survey gives a sense of the pathogens that members are currently interested in and some of the dry and wet lab skills required in bioinformatics. These findings are helpful in planning and implementing new projects and building stronger networks among members.

Do have a complete read to enjoy these and other updates.

Ranga Matima

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Data Repositories Working Group: Welcome to our new Chairs!

Arthur Shem Kasambula and Dr. Emma Hodcroft have joined PHA4GE’s Data Repositories Working Group as co-chairs, aiming to advance tools and databases like Pathoplexus for improved pathogen data sharing. Their efforts will drive consensus-driven solutions and technical recommendations to enhance usability and integration across global data systems.

Introducing Pathoplexus

We are announcing Pathoplexus, a specialised genomic database for viruses of public health importance. By combining modern open-source software with transparent governance structures, Pathoplexus fills a niche within the existing genomic sequencing database landscape, aiming to meet requests from both data submitters and users and striving to improve equity.

2024 PHA4GE Member Survey – Report

In April and June 2024, we invited all PHA4GE members to participate in a survey to ensure PHA4GE is providing opportunities that align with your passions and expertise. The results have been compiled into a short report.