Participate in ethics and data sharing community  | ​  Learn More 

Working Group

Data Repositories

Focus Areas

Sequence submission, query and retrieval

Repository-based tools

Databases

APIs

Public health engagement and interaction with INSDC

Data sharing and governance

FAIR Principles

Overview

Inception: August 2024

# of Members: 20+

Chair: Emma Hodcroft
Swiss Tropical and Public Health Institute, Switzerland

Vice-Chair: Arthur Shem Kasambula
Makerere University, Uganda

Contact: [email protected]

Working Group Description

This workgroup will build upon existing repository tools, APIs, and databases, including the newly-launched Pathoplexus platform. By collaborating with repository staff, stakeholders, and the Pathoplexus community, the group aims to develop consensus-driven solutions for public health-relevant processes and data structures. Taking into account the development roadmaps of NCBI, DDBJ, ENA, and Pathoplexus, we will provide technical recommendations to improve the utility, usability, and integration of Pathoplexus within the broader landscape of pathogen data systems.

Projects

Pathoplexus is a open-source database designed to enhance the sharing and analysis of human viral pathogen genomic data. Developed in response to the growing need for specialized viral databases, Pathoplexus aims to offer the features needed for the research community to share and explore datasets for viruses of public health importance. By leveraging new open-source software, Pathoplexus provides a robust and user-friendly platform for scientists and public health professionals.

Kathryn Holt

LSHTM

Chaoran Chen

ETH Zurich

Sunday Ayuba Buru

Kaduna State University

Emma Hodcroft

Swiss TPH

Nyasha Chin'ombe

University of Zimbabwe

Tesfahun Wubetu

Addis Ababa University

Arthur Shem Kasambula

Makerere University

Jamie Southgate

PHA4GE

Theo Sanderson

Francis Crick Institute

Eneida Hatcher

NIH/NLM/NCBI

Ruth Timme

US Food and Drug Administration

Related Research

Arthur Shem Kasambula and Dr. Emma Hodcroft have joined PHA4GE’s Data Repositories Working Group as co-chairs, aiming to advance tools and databases like Pathoplexus for improved pathogen data sharing. Their efforts will drive consensus-driven solutions and technical recommendations to enhance usability and integration across global data systems.

We are announcing Pathoplexus, a specialised genomic database for viruses of public health importance. By combining modern open-source software with transparent governance structures, Pathoplexus fills a niche within the existing genomic sequencing database landscape, aiming to meet requests from both data submitters and users and striving to improve equity.