Coming Soon
Sepsis, particularly neonatal sepsis, remains a pressing global health challenge with significant mortality and long-term impacts. Genomic epidemiology and AMR (antimicrobial resistance) profiling provide opportunities to improve surveillance and clinical decision-making. PHA4GE is working with leading networks and researchers to establish metadata standards that will enable consistent, interoperable, and actionable genomic data for sepsis research and control.
Current efforts in sepsis surveillance face fragmented data standards, limited harmonisation with laboratory information systems, and insufficient integration across international initiatives. Without clear metadata frameworks and aligned tools, the potential of genomic epidemiology in sepsis, especially in detecting AMR markers cannot be fully realised. Developing robust, community-driven standards is essential to ensure interoperability, reproducibility, and practical uptake in both high- and low-resource settings.
PHA4GE is engaging partners including NeoNet-Africa, Klebgen, KlebNET-GSP, SeqAfrica and SEDRIC alongside community experts. The initiative will focus on:
Through collaboration and alignment, this project will enable reproducible, harmonised sepsis genomic data that strengthens AMR surveillance and supports better public health responses.
Coming Soon