This Working Group brings together infrastructure engineers, bioinformaticians, IT teams, and public health practitioners to align on practical infrastructure solutions.

Key focus areas include:

• Cloud computing and storage, including hybrid and multi-cloud approaches

• On-premise high-performance computing (HPC) and local server environments

• Field-portable systems for low-resource or disconnected settings

• Containerization and orchestration (e.g. Docker, Singularity, Kubernetes)

• Networking and connectivity models, including intermittent or low-bandwidth environments

• Access control, monitoring, and security considerations

• Implementation, sustainability, and support models

• Workforce requirements and procurement strategies

Key deliverables include:

• Best practices for scalable, provider-agnostic cloud workflows, including hybrid and multi-cloud environments

• Recommendations and requirements for maintaining a core set of deployable containers and services

• Guidance on containerization, orchestration, and management for public health bioinformatics

• Infrastructure and staffing recommendations for routine genomic surveillance workflows

• Reusable strategies for cost-efficient cloud deployment and resource management (e.g. elastic computing, serverless approaches)